In December 2008 Karen Malkin-Lazarovitz tested positive for a BRCA gene mutation that gave her an 87% lifetime risk of developing breast cancer and a 40% risk of developing ovarian cancer. She decided to have surgeries that would reduce her risk of developing those cancers, to under 4%. She underwent a prophylactic hysterectomy and ovary removal, as well as a preventative double mastectomy with reconstruction.
She’s since started a hereditary cancer support group, which has grown to be the largest global support group of its kind. She now dedicates her time to educating the public on the risks of such cancers.